Posted on by Alex Russell

Disease and Pests: Harpin Proteins

In this tutorial, we re-visit Harpin proteins, particularly Harpin αβ protein,

Here we look at a particular product, the 'HALO Harpin Protein', an alpha/beta protein extracted from plants called Harpin αβ protein, an activated protein technology blended with essential micronutrients, these micronutrients are chelated within the blend to ensure a slow consistent delivery of nutrients over the course of 3-10 days.

Halo Harpin Protein
  • Increases plant resilience
  • Reduces on set of Botrytis
  • Can help prevent end rot on blossoming crops
  • Increase in fruit sugars
  • Calcium absorption rate increases by more than 20%
  • Reduces bacteria wilt
  • A.S.A. Tested
  • Cornell University tested


Harpin proteins are applied via foliar mist and can also be used as a seed or tuba scarification/pre-treatment.

Studies have shown Harpin αβ protein to have a significant effect on activating a plants defense response to disease, pests and bacteria, helping fight off these attacks with much greater success. Disease pests are not expected to develop resistance to Harpin αβ.


Mode of Action

"Harpin αβ does not act directly on disease organisms, nor does it permanently alter the DNA of treated plants. Instead, Harpin αβ activates a natural defense mechanism in plants, referred to as systemic acquired resistance (SAR). Harpin αβ and the Harpin protein registered in the year 2000 are structurally and functionally similar. Harpin αβ protects against certain bacterial, viral, and fungal diseases; soil-borne pathogens; and harmful nematodes and insects. Harpin αβ protein also enhances plant growth and vigor, and increases the yield for a variety of crops, including vegetables, trees, and ornamentals.

In addition to protecting against various diseases, Harpin αβ enhances plant growth and improves yield and quality of many crops, including food crops, turf, and ornamentals." [1]


Risks to human health and environment

According to the EPA's study [1] of Harpin Protein αβ, "Human health risks posed by Harpin αβ are expected to be minimal to nonexistent. No harmful effects were seen in mammalian toxicity tests. Environmental risks to wildlife and beneficial insects are also expected to be minimal to nonexistent."